비강 및 상악동의 도립 유두종에서 유래된 편평세포암 1례 (유세포계 측검 색 의 추적 관찰)

Inverted papilloma has been known their specific characteristics of local aggressiveness, recurrence after prompt treatment and malignant transformation. The malignant transformation rate was variable from 2% to 53%. But there was no clinical prognostic indicator in their malignant potency. DNA flow cytometry may appreciate biologic behavior of the tumor. Clinicopathologic aspect of the tumor and the degree of aneuploidy is helpful to understand the malignant potency. Recently, the authors experienced the one case of maxillary squamous cell carcinoma arising from inverted papilloma, previously operated 4 times and reported with DNA flow cytometric results. It is suggested that DNA flow cytometry may be prognostic indicator in malignant transformation of inverted papilloma.