괴사성 임프절염(기구찌병) 3례

Subacute necrotizing lymphadenitis, or Kikuchi’s disease is a newly recognized disease of unknown origin, occurred usually in young woman and mostly resolved spontaneously without treatment within a few months. Clinically, characteristic symptoms and signs were local lymph node enlargement, sometimes accompanied by tenderness, fever, weight loss, leukopenia, and elevated erythrocyte sedimentation rate. Lymph node biopsy reveals areas with flank cellular necrosis, karyorrhexis, and absence of plasma cell. The histologic features of subacute necrotizing lymphadenitis are distinctive, but these can be confused with those of malignant lymphoma and tuberculosis.

We present three cases of subacute necrotizing lymphadenitis and discuss their diagnosis and treatment.