Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery
종설
괴사성 임프절염(기구찌병) 3례
김태철1, 김영민1, 박영민1, 안혜경*
Three Cases of Subacute Necrotizing Lymphadenitis(Kikuchi’s Disease)
Tae Cheol Kim1, Young Min Kim1, Young Min Park1, Hae Kyung Ahn*
1Department of Otolaryngology, College of Medicine, Hallym University
*Pathology, College of Medicine, Hallym University
© Copyright 1993 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Published Online: May 31, 2020
ABSTRACT
Subacute necrotizing lymphadenitis, or Kikuchi’s disease is a newly recognized disease of unknown origin, occurred usually in young woman and mostly resolved spontaneously without treatment within a few months. Clinically, characteristic symptoms and signs were local lymph node enlargement, sometimes accompanied by tenderness, fever, weight loss, leukopenia, and elevated erythrocyte sedimentation rate. Lymph node biopsy reveals areas with flank cellular necrosis, karyorrhexis, and absence of plasma cell. The histologic features of subacute necrotizing lymphadenitis are distinctive, but these can be confused with those of malignant lymphoma and tuberculosis.
We present three cases of subacute necrotizing lymphadenitis and discuss their diagnosis and treatment.
Keywords: Kikuchi’s disease