대장암 수술 후 항암치료 중 상악골에 발생한 침습적 모균증 1예

The clinical manifestations of mucormycosis are similar to those of fulminant rhinosinusitis. It is also known as rhinocerebral mucormycosis because it begins from the sinonasal cavity and invades into the orbit or brain rapidly. Fungi in contact with sinonasal mucosa penetrate into tissue, and form blood clots in the vascular endothelium widely by inducing the ischemic lesion. In general, healthy people are not susceptible to them. However they progress rapidly in diabetic or immunocompromised patients. In this study, we report a case of 59-year-old woman with diabetes mellitus who developed invasive mucormycosis during postoperative chemotherapy for colorectal cancer and treated with administration of antifungal agent after partial maxillectomy. (J Clinical Otolaryngol 2013; 24:276-279)