Journal of Clinical Otolaryngology Head and Neck Surgery

The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery

J Clin Otolaryngol Head Neck Surg 2013; 24(2):276-279

pISSN: 1225-0244, eISSN: 2713-833X

DOI: https://doi.org/10.35420/jcohns.2013.24.2.276

증례

대장암 수술 후 항암치료 중 상악골에 발생한 침습적 모균증 1예

박찬휘¹, 이일우¹, 이정훈¹, 홍성룡¹^,²^,^*

Invasive Mucormycosis of the Maxilla Developed during Adjuvant Chemotherapy for Colon Cancer

Chan-Hwi Park¹, Il-Woo Lee¹, Jung-Hoon Lee¹, Sung-Lyong Hong¹^,²^,^*

¹부산대학교병원 이비인후과

²의생명연구원

¹Departments of Otorhinolaryngology-Head and Neck Surgery, Busan, Korea

²Biomedical Research Institute, Pusan National University Hospital, Busan, Korea

^*교신저자: 홍성룡, 602-739 부산광역시 서구 구덕로 179 부산대학교병원 이비인후과 전화 :(051) 240-7335·전송:(051) 246-8668 E-mail:st-dragonhong@hanmail.net

© Copyright 2013 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Sep 26, 2013; Revised: Oct 22, 2013; Accepted: Nov 14, 2013

Published Online: May 31, 2020

ABSTRACT

The clinical manifestations of mucormycosis are similar to those of fulminant rhinosinusitis. It is also known as rhinocerebral mucormycosis because it begins from the sinonasal cavity and invades into the orbit or brain rapidly. Fungi in contact with sinonasal mucosa penetrate into tissue, and form blood clots in the vascular endothelium widely by inducing the ischemic lesion. In general, healthy people are not susceptible to them. However they progress rapidly in diabetic or immunocompromised patients. In this study, we report a case of 59-year-old woman with diabetes mellitus who developed invasive mucormycosis during postoperative chemotherapy for colorectal cancer and treated with administration of antifungal agent after partial maxillectomy. (J Clinical Otolaryngol 2013; 24:276-279)

Keywords: 모균; 진균; 부비동염; 면역기능저하숙주; 항진균제

Keywords: Mucor; Fungi; Sinusitis; Immunocompromised host; Antifungal agents