돌발성난청에서 혈청 아연 농도 및 혈액검사 소견

Backgroud and Objective: Sudden deafness is defined as an isolated entity of abrupt onset of sensorineural hearing loss without definitive cause. The pathogenesis is not know yet, but there are several presumptive causes, for example, vascular occlusion, viral infection, autoimmune disorder, ototoxic drug, membrane rupture, and so on. Then we studied about the laboratory results of sudden deafness to know the presumptive étiologie factor and the relationship between one and prognosis. Material and Method: We performed retrospective study about laboratory parameters in 250 sudden deafness. It contained hemostatic factor, infectious markers, electrolytes, hepatic and renal function, viral markers with serum protein and serum immunoglobulin. Results: Sudden deafness was not related to hemostatic factors. Also, we couldn't examine the relationship between abnormal renal/hepatic function and the prognosis. But, the sudden deafness usually had high zinc level (74%) that had good prognosis than normal zinc level (p<0.05). Conclusion: The serum zinc level can use a good prognostic factor in sudden deafness. Other laboratory parameter could be helpful to exclude the underlying and associated disease but not related to the prognosis except serum zinc level.