원저

돌발성난청에서의 바이러스감염에 관한 연구

전경명1, 고의경1, 노환중1, 이지원1, 김서규1, 문영일1, 한진영2
Kyong-Myong Chon1, Eui-Kyung Goh1, Hwan-Jung Roh1, Ji-Won Lee1, Seu-Gyu Kim1, Young-II Moon1, Jin-Young Han2
Author Information & Copyright
1부산대학교 의과대학 이비인후과학교실
2동아대학교 의과대학 임상병리과학교실
1Department of Otolaryngology, College of Medicine, Pusan National University
2Department of Clinical Pathology, College of Medicine, Dong-A University

© Copyright 1995 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: May 31, 2020

ABSTRACT

Some studies for etiology of sudden deafness reveal ‘unknown origin’ but it is possible for apparent or inapparent viral infections to cause sudden hearing loss. There are many presumed causes of sudden deafness: congenital, inflammatory, vascular, neoplasm, metabolic, trauma, functional and membrane rupture. Documentations showing the cause-and-effect relation to sudden sensorineural hearing loss clarified that first, flu-like symptom commonly observed as preceedings and seasonal variation of incidence in sudden deafness second, serologic data for several causative viruses third, histopathologic changes found in experimental viral labyrinthitis.

We performed retrospective study about clinical data in 20 sudden deafness patients and measured viral antibody titer based on enzyme-linked immunosorbant assay and hemaglutinin inhibition method about Measle, Mumps, Influenza A · B, Rubella, Herpes simplex, and Varicella zoster viruses. We also compared the results of audiologic and serologic studies between presumed virus infected patients and non-infected patients.

The results were as followings:

  1. Among 20 subjects, 9(45%) subjects were serollogically proved viral infection: 2 (10%) subjects presumed recent infection due to positive IgM antibody and 7(35%) subjects presumed infection due to increase in IgG antibody titers.

  2. There were no significant difference in hearing gain after termination of treatment between viral infected group(23.6±15.9 dB) and non-viral infected group(18.0±22.2 dB).

  3. viral infection is strongly suspected as a causative factor of sudden deafness.

Keywords: Virus; Sudden deafness


임상이비인후과 학술상 공지


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대한이비인후과학회 부산울산경남지부회에서는

회원분들의 학술 연구를 장려하는 의미에서 

2022년도부터 학술상을 신설해 수여하고자 합니다. 

 

임상이비인후과 학술상

1. 2022년에 본 학술지에 게재된 논문중

인용횟수 및 학술적 가치가 높은 연구주제에 대해

편집위원회에서 선정 후 수여

2. 수상자는 논문의 교신저자로 함

3. 시상 - 상장 및 상금 50만원

4. 시상일 - 추후 공지

5. 편집위원회에서 선정하므로 별도의 신청 필요 없음

 

- 관련문의 

 임상이비인후과 편집위원회  jco.hns.1990@gmail.com


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