기니픽의 체온에 따른 청성뇌간유발반응의 변화에 대하여
Published Online: May 31, 2020
Abstract
The auditory brainstem response (ABR) has been used to determine the threshold and to evaluate the retrocochlear lesions and etc. However, various nonpathological conditions such as core temperature, age, noise trauma and methods of reducing body movement artifact could affect the response.
To elucidate the relation between the auditory brainstem response and body temperature, ABRs were recorded in 16 guinea pig with changing the temperature. A 90dB HL dternating click sound was delivered through the insertion type tube stimulartor.
The latencies of I, III,IV,and interpeak latencies(IPLs) I -III, III-IV,I -IV were significantly shortened while the body temperature increased from 32 to 41°C. However the amplitudes were not significantly changed with different temperatures. The mean value of IPLs at 37°C were 1.52±0.30(msec) in I-III, 1.18±0.74(msec) in III-IV,and 2.70土0.66(msec) in I -IV, respectively.
The simple regression slope for IPLs I-III,III-IV,and I -IV were 0.06,0.03,and 0.09.
These results showed that the influence of the body temperature shoud be accounted in the interpretation of ABR in the guinea pig.