괴사성 림프절염 4례

Histiocytic necrotizing lymphadenitis(HNL), or Kikuchi’s disease, is a newly recognized disease of unknown origin, that causes cervical lymphadenitis and may be mistaken for malignant disease both clinically and histologically. This disease is a benign self-limiting course and occurs predominantly in young aduU. Common manifestations are cervical lymph nodes enlargement, fever, weight loss and night sweats. Lymph node biopsy reveals areas with frank cellular necrosis, karyorrhexis, infiltration of lymphocyte and granulocytopenia. Symptoms resolve spontaneously and lymph node biopsy is necessary to excluded malignant disease and systemic lupus erythematosis.

Authors report the clinicopathologic study about 4 patients, 4 males, who were diagnosed as HNL on exeisional and fine needle aspiration biopsy.