증례

Quadruple Primary Malignancies in an Old Male Smoker Treated with Cooperative Surgery

Jeon Yeob Jang1, Wonjae Cha1, Hyun Sung Kim2, Jeong Su Cho3,*, Soo-Geun Wang1
Author Information & Copyright
1Department of Otorhinolaryngology-Head and Neck Surgery, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea
2Surgery, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea
3Thoracic and Cardiovascular Surgery, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea
*교신저자: 조정수, 49241 부산광역시 서구 구덕로 179 부산대학교 의과대학 부산대학교병원 흉부외과학교실 전화 :(051) 240-7267·전송 :(051) 243-9389 E-mail:drmozart@hanmail.net

© Copyright 2015 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Sep 30, 2015; Revised: Oct 23, 2015; Accepted: Nov 27, 2015

Published Online: May 31, 2020

ABSTRACT

The patients with head and neck cancers are frequently elderly with history of smoking that may harbor possibilities of multiple primary malignancies. Recent use of PET-CT as an initial diagnostic tool facilitates the finding of unexpected primary malignancies. Here we present a case of quadruple primary malignancies treated with cooperative surgery. A 66 year-old male presented with sore throat. He was identified as a current smoker and had a history of alcohol ingestion. Physical examination followed by office-based biopsy revealed supraglottic squamous cell carcinoma. Imaging studies including PET-CT found multiple suspicious malignant lesions involving thyroid gland, esophagus, sigmoid colon as well as the larynx. Further multidisciplinary consultation suggested that all of the evaluation lesions were primary malignancies without evidence of systemic spread. The patient underwent cooperative surgery ; supraglottic partial laryngectomy with neck dissection for supraglottic cancer, left hemithyroidectomy for thyroid cancer, Ivor Lewis operation for esophageal cancer, lower anterior resection for colon cancer. Careful postoperative care was provided without a complication. Office-based observation has been ongoing without an evidence of recurrence. (J Clinical Otolaryngol 2015;26:312-316)

Keywords: Quadruple primary cancer; Multiple primary cancer; Head and neck cancer