설하선에서 발생한 상피-근상피암종 1예

Epithelial-Myoepithelial carcinoma (EMC) is rare salivary gland neoplasm with a propensity to arise from major salivary gland, particularly of the parotid. EMC shows a characteristic biphasic population of epithelium and myoepithelium but shows various cytologic and histologic features, so this low grade malignancy can cause diagnostic confusion during workup and also frequently be misdiagnosed as other high grade salivary malignancy. Therefore histopathologic diagnosis is essential and immunohistochemistry is an important tool when making differential diagnosis. The treatment of choice is wide surgical excision, and long-term follow up is necessary to evaluate local recurrences. We herein report a case of EMC arising in a sublingual gland with a review of the relevant literature. (J Clinical Otolaryngol 2014;25:75-79)