하인두암의 경구강 레이저 수술

Background and Objectives: Recently, organ-preserving transoral CO2 laser surgery have been introduced for hypopharyngeal cancer. The aim of this study was to define when CO2 laser surgery of hypopharyngeal cancer is indicated and to evaluate the oncologic local control rate, functional results, and postoperative complications. Subjects and Method: A retrospective review of 6 patients undergoing transoral CO2 laser microsurgery for the treatment of squamous cell carcinomas of the hypopharynx involving posterior pharyngeal wall (2 patients), pyriform sinus (4 patients) from May 2006 to December 2010 was undertaken. There were three patients with staging T3, underwent transoral CO2 laser surgery to remove residual cancer after the induction chemotherapy. The median follow-up interval was 32 months. Results: Five out of six cases showed no local recurrence. One patient with pyriform sinus cancer died with the local recurrence and lymph node metastasis, and local control rate during follow up was 83.3%. One patient died due to brain metastasis in the postoperative 24 months, other patient died due to second primary esophageal cancer in the postoperative 36 months. There were 2 cases of surgical complications; dysphagia due to temporary esophageal stricture and primary site’s bleeding. Conclusions ?Although more number of cases and time are needed, in some carefully selected cases of the early staging and advanced hypopharyngeal cancer after induction chemotherapy, transoral CO2 laser surgery can be one of the choice. (J Clinical Otolaryngol 2011;22:72–81)