안와, 접형동, 두개저를 침범한 비부비동 B세포 림프종 1예

Primary sinonasal B cell lymphoma is usually presenting with unilateral nasal mass. Mainly its pathologic subtypes by WHO classification are NK/T cell and diffuse large B-cell type in order of frequency. A-65-year-old-male came to emergency room, complaining with loss of visual acuity and ocular pain for one month. PNS CT showed right unilateral nasal mass involving the orbit, skull bass and the sphenoid sinus. We performed the endoscopic sinus surgery, final pathologic diagnosis was diffuse large B-cell lymphoma. He received six cycles of R-CHOP chemotherapy, and gained complete remission. No recurrence is observed until three years. We report a unique case of sinonasal lymphoma with related literature review. (J Clinical Otolaryngol 2010;21:261-264)