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Pleomorphic adenoma is the most common type of benign epithelial salivary tumor. It appears, in decreasing frequency，in the parotid gland, submandibular gland and palate. Yet the presence of this neoplasm in the upper respiratory tract is rare. Batsakis stated that within the upper respiratory tract the most favored site of origin is the nasal cavity, followed by the maxillary sinus and the nasopharynx.

Recently authors experienced one case of pleomorphic adenoma of the cartilagenous nasal septum, which was removed through alatomy approach and it is presneted with review of the literatures.