측두골, 장골, 경추를 침범한 다발성 골수종 1예

Multiple myeloma (MM) is a neoplastic proliferation of monoclonal plasma cells within the hematopoietic bone marrow. Symptoms of MM are related to osteolytic lesions, to the replacement of bone marrow by the neoplastic process and to renal insufficiency. Involvement of the temporal bone has been reported to occur in the terminal stage of MM. However, at this stage, otological symptoms are overshadowed by the manifestations of diffuse skeletal disease. There has been only one case of MM involving the temporal bone reported in Korea. Here we report a patient who presented with otalgia due to the plasmacytoma of temporal bone and finally diagnosed as multiple myeloma. (J Clinical Otolaryngol 2008;19:200-204)