두경부 우상암종의 임상양상

Background and Objectives: Verrucous carcinoma is a well- differentiated squamous cell carcinoma with minimal cytologic atypia. Although usually curable at an early stage, it can be locally aggressive if left untreated. This study provides the clinical features and treatment outcome of verrucous carcinoma of the head and neck. Materials and Method: From 1991 through 2001, 10 patients received initial treatment for verrucous carcinoma of the head and neck at Keimyung university Dong-san hospital. We retrospectively reviewed the presentation, diagnosis, treatment and outcomes in these patients. All cases were confirmed by histologic examination. Results: All but two patients were men, and most were smokers. Tumors originated most frequently in the oral cavity (50%) and larynx (30%). The TNM classification (AJCC 2002) was Ti in 5 patients, T2 in 3 and T3 in 2. Eight patients were treated by surgical excision alone and one patient was treated by radiation after surgery. Local recurrence without neck involvement occurred in 2 of the 10 patients. The overall cumulative survival rate was 100%. Conclusion: When discovered early, verrucous carcinoma of the head and neck can be treated effectively with wide local excision with good results, it is different from classic squamous cell carcinoma. (J Clinical Otolaryngol 2008;19:79–82)