양측 주타액선에 발생한 Kimura씨 병 치험 1례

Kimura’s disease is an uncommon chronic inflammatory disorder involving subcutaneous tissue, predominantly the head and neck region. This disease is more prevalent in Asian young men, associated with regional lymphadenopathy, salivary gland involvement, peripheral hypereosinophilia and increased serum IgE and his- topathologically diagnosed. Although the etiology is unknown, it is possibly proposed as a pathogenetic mechanism that an unknown antigen stimulates mast cells to release IgE, which initiates a type I hypersensitivity reaction with the release of lymphokines. The treatment includes surgical excision, steroid therapy, radiation and cytotoxic therapy. We report one case of Kimura’s disease involving both submandibular gland and one parotid gland which were successfully excised. (J Clinical Otolaryngol 2008;19:119–122)