위식도역류증과 인후두이상감증과의 상관관계

Background and Objectives: Globus pharyngeus is a choking sensation, as of a lump in the throat. Although otolaryngolosists are often confronted with this condition, they still do not complete understand the etiologies of globus pharyngeus. Recently reserchers have come to believe that gastroesophageal reflux (GER) are the most important etiologic factor causing globus pharyngeus. In an attempt to verify this current belief, the authors performed a prospective study in patient who complained of globus sensation in the throat. Materials and Method: All 30 patients with globus symptoms met the Rome II criteria. They underwent telelaryngoscopy, gastroesophagoscopy and ambulatory 24 hr pH monitoring. Result: GER was diagnosed in 20% of the tested patient. On telelaryngoscope, Reflux finding score (RFS) was 2.83 in GER patients and 4.0 in non-GER patients. On gastroesophagoscope, the number of patients were decreased along the LA Classification grade. On ambulatory 24 hr pH monitoring, the number of patients were decreased along the %time. These results consequently suggest globus pharyngeus dose not correlate with GER. Conclusion: In contrast to the current belief, GER should be regarded as just one of the possible etiologic factor, and it is necessary to evaluate the further etiologic factors. (J Clinical Otolaryngol 2005;16:253–257)