설하선에 발생한 호산성 세포 암종 1예

The oncocytic adenocarcinoma of salivary gland origin is extremely rare. Histopathologic features of this tumor is characterized by oncocytes with marked cellular atypia, frequent mitoses, destruction of adjacent structures, perineural or intravascular invasion and distant or regional metastasis. The treatment is the surgical excision and if there are infiltration of lymph nodes, the neck dissection is recommended. A 55-year-old woman presented with cystic mass on mouth floor for 1 year. The tumor was excised via intraoral approach. Pathologic findings showed that the tumor was lined by proliferated oncocytic cells with atypia and showed infiltrative growth into fibrotic capsule and vascular invasion. We discuss the clinical and histopathological features of the oncocytic adenocarcinoma of the sublingual gland with the review of the literature. (J Clinical Otolaryngol 2004;15:320-322)