후신경아세포종 1예

Olfactory neuroblastoma is uncommon neuroendocrine malignant tumor originated from olfactory epithelium of neural crest in the upper portion of nasal cavity. This tumor account for 2% of all malignant nasal neoplasm and early involves the cribriform plate and rapidly penetrate into the anterior cranial fossa. The meatastasis develope in the neck, lymph node, lung, bone and so on from 20% to 42%. Although the principle of treatment is not established yet, combined therapy of surgery and radiation is generally recommended. We have experienced one case of neuroblastoma localized in the nasal cavity and nearly completely removed via transpalatal and transnasal approach followed by radiotherapy. At this time the tumor is not recurred and any complication has been not developed, so we report this case with review of the literature. (J Clinical Otolaryngol 2002;13:130-134)