후두 편평세포암종의 방사선치료 후 경부에 발생한 육종양 암종 1례

Background: Sarcomatoid carcinoma is a rare and bizarre neoplasm with divergent differentiation. It is a squamous cell carcinoma with spindle cell and giant cell component and may be misinterpreted as a sarcoma. Because of its rarity, its diagnosis, optimum treatment, and prognosis remain controversial. Case: A 60-year-old male presented with an enlarging fist-sized right neck mass which developed 1.5 year after radiation therapy for the laryngeal cancer. Pathology revealed a mixture of malignant squamous and spindle cells with positive immunohistochemical staining for vimentin, myoglobin and desmin, but negative reaction for cytokeratin. Conclusion: We experienced a case of sarcomatous carcinoma in the neck which developed after radiation therapy for the laryngeal cancer. (J Clinical Otolaryngol 1999;10:105-109)