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만성비염에서의 비즙 및 비점막세포검사
Published Online: May 31, 2020
Abstract
Author has studied nasal cytologies by smear and by nasal mucosa smear for 23 allergic rhinitis patients and 35 nonallergic rhnitis patients with light microscopic examination.
And the results were as follows;
Eosinophilia in nasal smear was 12 patients(52.2%) in the 23 allergic rhinitis and 12 patients(34.3%) in the 35 nonallergic rhinitis.
Eosinophilia in nasal mucosa smear was 16 patients(69.6%) in the 23 allergic rhinitis and patients(51.4%) in the 35 nonallergic rhinitis.
Increased basophilic cells in nasal mucosa smear was 13 patients(56.5%) in the allergic rhinitis and 9 patients(25.7%) in the nonallergic rhinitis.
Increased eosinphiles and/or basophilic cells in nasal mucosa smear was 21 patients(91.3 %) in the allergic rhinitis and 22 patients(62.9%) in the nonallergic rhinitis.
In nasal mucosa smear of the allergic rhinitis, mean number of eosinophil was 16.5 cells and mean number of basophilic cell was 6.1 cells, and then mean of eosinophil was greater than that of basophilic cell.
In nasal mucosa smear of the nonallergic rhinitis, mean number of eosinophil was 9.4 cells and mean number of basophilic cells was 3.9 cells, and also mean number of eosinophil was greater than that of basophilic cells.
The mean number of nasal mucosa eosinophil in (+) eosinophilia in nasal smear was 10.0 cells, (++) eosinophilia was 12.9 cells, and (+++) eosinophilia was 23.5 cells, and then the number of nasal mucosa eosinophil in case of (+++) eosinophilia was greater than that of (+) eosinophilia case.
The mean number of nasal mucosa basophilic cell in (+) eosinophilia in nasal smear was 2.7 cells, and (++) eosinophilia was 7.3 cells, and (+++) eosinophilia was 9.3 cells, and then the number of nasal mucosa basophilic cell in case of (+++) eosinophilia was greater than that of (+) eosinophilia case.
In the cases of below 4% of eosinophil in peripheral blood，the mean number of nasal mucosa eosinophil was 9.9 cells, and in the case of above 5% of eosinophil was 14.9%, but there was no statistical significance between these two numbers(p>0.05).
In the cases of below 199 IU of total Ig E，the mean number of nasal mucosa eosinophil was 8.8 cells, and in the cases of above 2000 IU of total Ig E was 8.5 cells, and so there was no difference.
And so author concluded that nasal mucosa smear is more reliable test than nasal smear for the diagnosis of allergic and nonallergic rhinitis. And the number of nasal mucosa eosinophil is correlative to the number of eosinophil in nasal smear.