Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery
종설

후두, 갑상선, 위에 발생한 다발암 1례

김승권1, 박상유1, 봉정표1, 윤병문1
Seung Kwon Kim1, Sang Yoo Park1, Jeong Pyo Bong1, Byoung Moon Yoon1
1연세대학교 원주의과대학 이비인후과학교실
1Department of Otolaryngology, Head and Neck Surgery Yonsei University Wonju College of Medicine

© Copyright 1993 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: May 31, 2020

ABSTRACT

Since Billroth (1869) first recognized that a single patient can develop simultaneous independant cancers, numerous series documenting multiple primary cancers have appeared in the literatures. Today, it is well documented that multiple primary cancers are also not unusual in patients with head and neck cancers, and can arise in related or different organs. Reported incidences of multiple primary cancers in head and neck cancers in various studies are in the range of 10∼35%. The histologic criteria for the diagnosis of multicentric neoplasms as originally described by Waren and Gates remains valid: 1) The neoplasms must be clearly malignant on histologic examination, 2) Each neoplasm must be geographically separate and distinct and not connected by either submucosal or intraepithelial neoplastic change, 3) The possibility that the second neoplasm represents a metastasis must be excluded.

Recently, we experienced a case of multiple primary cancers occured in the larynx (squamous cell carcinoma ), thyroid gland(papillary carcinoma), and stomach (adenocarcinoma) and report this case with brief review of literatures.

Keywords: Multipe Primary Cancers; Larynx; Thyroid Gland; Stomach