Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery
원저

인두 신경증과 위식도 역류의 상관관계에 대한 예비연구

최홍식1, 이승문1, 이상덕1, 홍원표1
Hong-Shik Choi1, Seung-Mun Lee1, Kwang-Moon Kim1, Won-Pyo Hong1
1연세대학교 의과대학 이비인후과학교실
1Department of Otorhinolaryngology Yonsei University College of Medicine, Seoul, Korea

© Copyright 1994 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: May 31, 2020

ABSTRACT

The term globus syndrome is used to describe those patients complaining of a discomfort or lump sensation in the throat without any determined causal factor. In order to study the relationship between globus syndrome and G-E reflux, 43 patients with globus symptom were evaluated. In our study, globus syndrome was two times more common in women, and most frequently in the fourth decade. Thirty three(77%) out of forty three patients had suffered gastrointestinal discomfort and 22 cases underwent UGI or endoscopic study previously. In a prospective trial, barium esophagogram and gastric scintigram were performed in 21 and 8 cases respectively in order to confirm the association between acid refulx and globus syndrome. Only two pathologic findings were diagnosed in barium study, whereas among the 8 cases who were examined with gastric scintigram 5 definite G-E reflux were noted. Antireflux medication was begun in all of the globus patients. 38 Cases(90%) were either significantly improved or rendered completely symptom-free after antireflux therapy. There was no difference in treatment effect in patients with globus only and patients with globus plus G-I discomfort.

Keywords: Globus syndrome; G-E reflux disease