Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery

알레르기 피부 단자 검사를 통한 흡입 항원과 음식 항원의 교차반응에 관한 분석

최치훈1,*, 노환중2, 구수권1, 송창윤1, 윤준호1, 김성원3
Chi Hoon Choi1,*, Hwan Jung Roh2, Soo Kweon Koo1, Chang Yoon Song1, Jun Ho Yoon1, Sung Won Kim3
1부산 성분도병원 이비인후과
2부산대학교 의과대학 이비인후과학교실
3부산 성분도병원 소아과
1Department of Otolaryngology, Busan National University, Busan, Korea
2Department of Otorhinolaryngology, College of Medicine, Busan National University, Busan, Korea
3Pediatrics, Saint Benedict Hospital, Busan, Korea
*교신저자: 최치훈, 602-739 부산광역시 동구 초량 3동 31-3 부산 성분도병원 이비인후과 전화: (051) 466-7001·전송: (051) 464-7271 E-mail:

© Copyright 2003 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Oct 25, 2003; Accepted: Dec 06, 2003

Published Online: May 31, 2020


Background and Objectives: A cross-reaction between foods and other allergens can be dangerous for asthmatics and, in severe cases, can result in the onset of anaphylatic shock and can aggravate symptoms for patients with atopic dermatitis and allergic rhinitis. This study aimed to find out the cross-reactivity between inhalant and food allergens through retrospective review of large number of cases showing positive allergen skin prick test. Materials and Method: Total 3,522 cases showing positive allergen skin prick test from Jan 1991 to Jan 2001 at Allergy Clinic in St. Benedict Hospital, Pusan, Korea were analyzed retrospectively. The allergen skin prick test consisted of 55 allergen, dividing into groups of house dust and mite, epithelials, pollens, molds, and foods. Results: The common offending allergen groups were dust and mites (56.0%), pollens (43.3%), and epithelials (39.3%) group. The most common offending single allergen was D. fariane (48.7%), followed by D. pteronyssinus, straw dust, cat fur, dog hair, alder and birch pollen, cockroach. The most common offending allergen among pollen group was alder pollen (26.2%), followed by birch, hazel, beech, mugwort. The common cross-reactive groups in patients with positive food allergen was dust and mites (51.1%), followed by pollens (35.7%), epithelials (20%), molds (10%) group. Common food allergens in patients with positive dust and mites allergen were shrimp and crab. And the common food allergens in patients with positive pollen group were bean and wheat for alder and hazel pollen, and were apple and peach for birch pollen. Conclusion: These result suggest a cluster of cross-reaction between dust and mites and crustacea like shrimp and crab, and between birch and apple, peach. (J Clinical Otolaryngol 2003;14:275-281)

Keywords: 교차반응; 피부 단자 검사; 부 알레르기 증후군
Keywords: Cross-reactivity; Oral allergy syndrome; Skin prick tests