Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery
원저

일차성 부갑상선기능항진증으로 수술적 치료를 받은 환자들에 대한 임상적 고찰

천용일1, 권현근1, 정다운1, 김재욱1, 김성동1, 신성찬1, 안상정2, 이진춘1, 이병주1,*, 김인주3
Yong-Il Cheon1, Hyun-Keun Kwon1, Dawoon Jung1, Jae-Wook Kim1, Sung-Dong Kim1, Sung-Chan Shin1, Sang-Jeong Ahn2, Jin-Choon Lee1, Byung-Joo Lee1,*, In-Joo Kim3
1부산대학교 의학전문대학원 이비인후과학교실
2성균관대학교 의과대학 강북삼성병원 병리과학교실
3내분비내과학교실
1Department of Otorhinolaryngology-Head and Neck Surgery, Pusan National University School of Medicine, Busan, Korea
2Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
3Division of Endocrinology, Pusan National University School of Medicine, Busan, Korea
*교신저자: 이병주,49241 부산광역시 서구 구덕로 179 부산대학교 의학전문대학원 이비인후과 학교실 전화: (051) 240-7536· 전송: (051) 246-8668· E-mail: voiceleebj@gmail.com

© Copyright 2017 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Sep 21, 2017; Revised: Oct 10, 2017; Accepted: Nov 08, 2017

Published Online: May 31, 2020

ABSTRACT

Background and Objectives: To evaluate the accuracy of ultrasound (US), computed tomography (CT) and 99Tc sestamibi scan (MIBI) for preoperative localization of solitary parathyroid mass in patients with primary hyperparathyroidism and analyze our surgical outcomes. Materials and Methods: In a retrospective study of 57 consecutive patients with primary hyperparathyroidism, all patients underwent parathyroidectomy from Jan. 2003 through Dec. 2013. Patients were performed ultrasound, computed tomography and Technetium-99m ses-tamibi scan before surgery. We also reviewed serum calcium, serum parathyroid hormone (iPTH), associated symptoms and pathologic results through electronic medical records (EMR). Results: All 57 patients were enrolled and they had single solitary parathyroid mass. In final pathologic results, 45 patients had solitary parathyroid adenoma, 7 patients had nodular hyperplasia and 5 patients were diagnosed as parathyroid cancer. In adenoma and carcinoma as a single nodule, accuracy of US was 95.2% (40/42), CT was 91.7% (44/48), MIBI was 81.5% (31/38). The most common symptoms were general weakness and nausea. Interestingly, asymptomatic hypercalcemia, incidentaloma were over the half patients. Postoperative numbness was observed in 4 patients and they were treated with calcium supplementation but not persisted longer than 4th day postoperatively. Conclusions : Our results show that the combination of US, CT, MIBI has benefits for preoperative localization of parathyroid mass in primary hyperparathyroidism and parathyroidectomy was useful for patients with primary hyperparathyroidism. (J Clinical Otolaryngol 2017;28:205–210)

Keywords: 일차성 부갑상선 기능항진증; 컴퓨터단층촬영; 초음파검사; 99mTc-sestamibi 스캔
Keywords: Primary hyperparathyroidism; Computed tomography; Ultrasonography; 99mTc-sestamibi