Journal of Clinical Otolaryngology Head and Neck Surgery

The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery

J Clin Otolaryngol Head Neck Surg 2012; 23(2):212-217

pISSN: 1225-0244, eISSN: 2713-833X

DOI: https://doi.org/10.35420/jcohns.2012.23.2.212

원저

저음역 돌발성 난청 환자에서 고실 내 덱사메타존 주입술 및 경구 스테로이드 병합 요법의 효과와 경구 스테로이드 복용량 조절을 위한 예비연구

임길채¹, 최승효¹^,^*

Preliminary Study for Control of Dosage of Oral Steroid and Effect of Intratympanic Dexamethasone Injection with or Without Oral Steroid as Treatment in Sudden Low Tone Hearing Loss

Gil Chai Lim¹, Seung Hyo Choi¹^,^*

¹제주대학교 의학전문대학원 제주대학교병원 이비인후과학교실

¹Department of Otolaryngology, School of Medicine, Jeju National University, Jeju Hospital, Jeju, Korea

^*교신저자: 최승효，690-716 제주특별자치도 제주시 아라동 1753-3 제주대학교 의학전문대학원 제주대학교병 원 이 비 인후과학교실 전화: (064) 717-716· 전송: (064) 717-1029 · E-mail： photen27@naver.com

© Copyright 2012 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Sep 28, 2012; Revised: Oct 19, 2012; Accepted: Nov 15, 2012

Published Online: May 31, 2020

ABSTRACT

Backgrounds and Objectives: Prevalence of low tone sudden sensorineural hearing loss (LSSNHL) has increased. However there was no definite treatment regimen of LSSLHL. The objective of this study is to analyze results of oral steroid therapy and intratympanic steroid injection (ITSI) as first line therapy for LSSLHL. Ad- dtionally, we compared side effects as treatment modality. Materials and Methods: We studied retrospectively 43 patients with LSSLHL at Jeju National University Hospital from March 2010 to July 2011. Under approval of patients we classified patients into 3 groups as treatment types. Patients to be treated with only ITSI were classified as group I (n=11), patients to be treated with ITSI and high dose oral methylprednisolone (1 mg/kg/day) were classified as group II (n=9) and patients to be treated with ITSI and half dose oral methylprednisolone (0.5 mg/kg/day) were classified as group III (n=23). Patients got 3 times of ITSI for a week. Before injection we warmed up dexamethasone (5 mg/mL) ample and we injected at posterosuperior portion of tympanic membrane. We carried out a pure tone audiometry (PTA) on the 1st day of their visit to hospital and before injection. We compared change of bone conduction threshold at 250, 500 and 1,000 Hz between 3 groups. Results: The hearing threshold of patients improved regardless of groups since the treatment. And there was no clinically significant differences in the outcome between groups. Conclusions: We could use ITSI as therapy in LSSLHL. If we used oral steroids for treatment of LSSLHL, we could consider reduction dosage of them. (J Clinical Otolaryngol 2012; 23:212–217)

Keywords: 돌발성 난청; 스테로이드; 고실 내 스테로이 드 주이술; 저음역

Keywords: Sudden hearing loss; Steroid; Intratympanic; Low frequency