Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery
원저

이명의 복합 약물치료 효과 비교

정지현1, 이선규1, 이호윤1, 변재용1, 박문서1, 여승근1,*
Ji Hyun Chung1, Sun Kyu Lee1, Ho Yun Lee1, Jae Yong Byun1, Moon Suh Park1, Seung Geun Yeo1,*
1경희대학교 의과대학 이비인후-두경부외과학교실
1Department of Otorhinolaryngology-Head and Neck Surgery, Kyung Hee University School of Medicine, Seoul, Korea
*교신저자: 여승근,130-702 서울 동대문구 회기동 1 경희대학교 의과대학 이 비 인후-두경부외과학교실 전화: (02) 958-8474·전송:(02) 958-8470 E-mail: yeo2park@yahoo.co.kr

© Copyright 2012 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Mar 12, 2012; Revised: Apr 05, 2012; Accepted: May 04, 2012

Published Online: May 31, 2020

ABSTRACT

Background and Objectives: Little is known about the mechanism that causes tinnitus and there is no definite treatment. In practice, a combination of drugs is preferred over a single drug regimen. The aim of this study is to evaluate and compare the effectiveness of 3 kinds of combination regimen for tinnitus. Subjects and Methods: We reviewed the records of 128 patients (156 ears) with tinnitus. Fifty of these patients were treated with ginkgo biloba extract, anti-platelet and anxiolytics. Another 50 patients were treated with ginkgo biloba extract, anxiolytics and vasodilator. Twenty-eight patients were treated with anxiolytics and vasodilator. Pre and post-treatment of 2-3 month statuses were analyzed by tinnitus handicap inventory (THI), visual analog scale (VAS) and Beck depression inventory (BDI). Results: Subjective tinnitus was improved in all three groups with no significant difference in tinnitus handicap inventory scores between the three observed groups. There was no difference between the response group and the non-response group in age, sex and tinnitus characteristics. The response group had a tendency to have lower BDI and normal hearing level compared to the non-response group. Conclusion: Patients with lower BDI and normal hearing level have a tendency to improve tinnitus after combined medical therapy, though there were no significant differences according to treatment regimens. (J Clinical Otolaryngol 2012;23:63–69)

Keywords: 이명; 복합 약물 치료
Keywords: Tinnitus; Drug therapy