Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery
원저

화학방사선요법 후 지속 혹은 재발한 비인두암 경부 전이의 평가와 경부절제술의 수술 결과

이호준1, 두형탁1, 유명훈1, 한주희2, 최승호1, 김상윤1, 남순열1,*
Ho Jun Lee1, Hyungtak Doo1, Myung Hoon Yoo1, Ju Hee Han2, Seung-Ho Choi1, Sang Yoon Kim1, Soon Yuhl Nam1,*
1울산대학교 의과대학 서울아산병원 이비인후과학교실
2전주예수병원 이비인후과
1Department of Otolaryngology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Presbyterian Medical Center, Jeonju, Korea
2Department of Otolaryngology, Presbyterian Medical Center, Jeonju, Korea
*교신저자: 남순열, 138-736 서울 송파구 풍납 2동 388-1 울산대학교 의과대학 서울아산병원 이비인후과학교실 전화:(02) 3010-3710·전송:(02) 489-2773· E-mail: synam@amc.seoul.kr

© Copyright 2010 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Aug 11, 2010; Revised: Aug 25, 2010; Accepted: Sep 24, 2010

Published Online: May 31, 2020

ABSTRACT

Background and Objectives: Nasopharyngeal carcinoma (NPC) patients may have persistent or recurrent neck masses without neither primary site recurrence nor distant metastasis after chemoradiotherapy. In this study, we reviewed our experiences in patients with neck masses underwent neck dissection. Materials and Methods: Between 1994 and 2005, 16 NPC patients with recurrent or persistent neck masses after chemoradiotherapy were reviewed retrospectively. Clinical and pathological parameters were investigated. Results: Persistent or recurrent neck masses were most frequently found in level II. Alleged neck masses were confirmed as metastatic carcinoma in 81.3%. Extranodal or adjacent soft tissue involvement was found in 25.0%. Narrower range of cervical metastases were found in 28.6%, wider range of cervical metastases were found in 42.8%, equal range of cervical metastases were found in 28.6% comparing with preoperative CT scan. Local control rate, disease specific 5 year survival rate and overall 5 year survival rate was 81.3%, 67.5% and 55.0% respectively. Distant metastasis was found in 25% during follow up. Conclusions: Neck dissection could be useful treatment alternative in managing NPC patients with persistent or recurrent neck masses after chemora- diotherapy. Neck dissection covering wider range of neck level would be better to perform because clinically unexpected wide spread of metastases were frequently found. (J Clinical Otolaryngol 2010;21:226–232)

Keywords: 지속; 재발; 비인두암; 화학방사선요법; 경부절제술
Keywords: Persistent; Recurrent; Nasopharyngeal carcinoma; Chemoradiotherapy; Neck dissection