Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery
원저

삼출성 중이염환자에서 혈중 항체치

은영규1, 여승근1,*, 변재용1, 차창일1
Young Kyu Eun1, Seung Geun Yeo1,*, Jae Yong Byun1, Chang Il Cha1
1경희대학교 의과대학 이비인후과학교실
1Department of Otolaryngology, College of Medicine, Kyung Hee University, Seoul, Korea
*교신저자: 여승근, 130-702 서울 동대문구 회기동 1번지 경희대학교 의과대학 이비인후과학교실 전화: (02) 958-8474·전송: (02) 958-8470 E-mail: khuent@khmc.or.kr

© Copyright 2006 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Jan 18, 2006; Accepted: Jun 13, 2006

Published Online: May 31, 2020

ABSTRACT

Background and Objectives: Inadequate antibody responses to pathogens in children may the increased susceptibility to acute otitis media. But it is not clear whether a correlation exists between otitis media with effusion and the presence the immunodeficiency of serum immunoglobulins IgG, IgA, IgM and IgE or not. Materials and Method: Fifty-six children with otitis media with effusion who had taken ventilation tube insertion and fifty two children for control group took part in the study at the Department of Otorhinolaryngology of the University of Kyung Hee from April 2004 to March 2003. Serum immunoglobulin levels were determined by nephelometry. And then the relationship between otitis media with effusion and immunodeficiency was evaluated. Result: No total IgG, IgA, IgM and IgE were detected below the normal level ; however, IgG was low at aged 5—9 years and IgM was low at aged 1—9 years who had otitis media with effusion compared with those levels of control. Conclusion: Lower immunoglobulins in children with otitis media with effusion suggest a generalized decreased antibody responses. Immunodeficiency of serum IgM and IgG may concerned with chronicity or intractability of otitis media with effusion. (J Clinical Otolaryngol 2006;17:56–60)

Keywords: 삼출성 중이염; 혈청항체(IgG, IgA, IgM and IgE)
Keywords: Otitis media with effusion; Serum immunoglobulin (IgG, IgA, IgM and IgE)