Table 6. Univariable factors associated with documented sinonasal morbidity (2011–2023)

Predictor N Odds ratio 95% CI p-value
Age (per 10 years) 314 0.94 0.78–1.14 0.530
Male sex 314 0.97 0.56–1.69 0.910
2017–2023 vs 2011–2016 314 0.95 0.56–1.61 0.838
Repeat vs initial recorded TSA 314 1.79 0.83–3.89 0.138
Diabetes mellitus 314 0.76 0.33–1.76 0.517
Smoking history 314 1.36 0.42–4.45 0.609
Prior rhinologic history 314 1.74 0.83–3.65 0.140
Nasal septal deviation 314 0.56 0.31–1.01 0.053
Operation time (per 30 min) 313 0.98 0.86–1.12 0.779
Documented perioperative CSF leakage 314 2.76 0.84–9.12 0.095
Macroadenoma vs microadenoma 293 0.78 0.26–2.29 0.645
Logistic generalized linear models used patient-cluster robust standard errors.
Models were univariable and exploratory; no multiplicity adjustment was applied.
N denotes procedures with data for each model.
No predictor met p<0.05.
Prior rhinologic history is not equivalent to an independently confirmed history of non-TSA nasal surgery.
CI, confidence interval; TSA, transsphenoidal approach; CSF, cerebrospinal fluid.