Table 1. The parameters for each IP specimen

Growth pattern	a. Endophytic
	b. Exophytic
Surface epithelium	a. Type of epithelium. Squamous metaplasia, columnar epithelium with cilia overlying squamous etaplasia, stratified squamous epithelium, or oncocytic columnar epithelium.
	a. Types of infiltrative inflammatory cells in the epithelium. Macrophages, polymorphonuclear leukocytes (PMNL), or eosinophils.
Stroma	a. Edema.
	b. Inflammation was “semiquantified” into three grades and the type of inflammatory cells, lymph follicles, and mast cells present were recorded.
	c. Seromucinous glands.
	d. Macrophages in the ductal epithelium.
	e. PMNL in the ducts.
	f. Basement membrane thickening.
	g. Eosinophils>10 per high-powered field. (HPF; 40× magnification).
	h. Dysplasia (semiquantified as mild, moderate, or severe [CIS]).
	i. Invasive carcinoma with invasion of stroma.

Adopted from Roh et al.⁴⁾ with permission of John Wiley & Sons.
CIS, carcinoma in situ.