Table 1. Summary of reported cases of renal cell carcinoma metastasis to the submandibular gland

Authors Sex/age Clinical manifestation Size of mass Other site metastasis PreOP FNA or CNBx Time after RCC Dx
Smits et al.9) F/60 Mobile mass 3 cm Parotid NA 7.5 years
Bedrosian et al.18) M/61 Asymptomatic nodule 0.9 cm No NA 0 years
Zoltie10) F/50 Tender pulsatile swelling 1 cm No NA 0 years
Ficarra et al.11) M/73 Painless lump (mouth) NA Bones, lung NA 13 years
Ham et al.12) M/59 Painless mobile mass 4 cm No Chronic inflammation 3 years
Moudouni et al.13) M/83 Painless swelling 4 cm No NA 10 years
Miah et al.15) F/61 Painless swelling 3 cm Thyroid Pleomorphic adenoma 7 years
Serouya et al.6) M/60 Nontender mass 1 cm No Metastatic RCC 9 years
Melloni et al.16) F/53 Painful, fixed swelling 4 cm No Warthin's tumor 4 years
Balaban et al.17) F/66 Mass 1.3 cm Parotid, liver, brain Metastatic RCC 1.5years
Majewska et al.5) F/97 Hard cohesive immobile NA NA NA NA
Higuera et al.4) F/74 Mass 1.5 cm Omentum, adrenal gland Metastatic RCC 11 years
PreOP: preoperative, FNA: fine needle aspiration, CNBx: core needle biopsy, RCC: renal cell carcinoma, Dx: diagnosis, NA: not applicable.