Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery
증례

일측 경부와 복부에 발생한 Rosai-Dorfman Disease 1예

안동빈1,*, 나경진1
Dongbin Ahn1,*, Kyung Jin Na1
1경북대학교 의과대학 이비인후-두경부외과학교실
1Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University,Daegu, Korea
*교신저자: 안동빈, 702-210 대구광역시 북구 호국로 807 경북대학교 의과대학 이비인후-두경부외과학교실 전화 :(053) 200-5777·전송:(053) 423-4524 E-mail:godlikeu@naver.com

© Copyright 2013 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Jun 17, 2013; Revised: Jul 18, 2013; Accepted: Sep 12, 2013

Published Online: May 31, 2020

ABSTRACT

Rosai-Dorfman disease is a rare lymph node disorder characterized by abnormal proliferation of histiocytes and usually presents with bilateral cervical lymphadenopathy. This disease has been poorly understood by otolaryngologists because of its rarity. We report an unusual case of a 61-year-old woman with Rosai-Dorfman disease involving one side of the neck and the abdominal cavity, which distinguishes our case from previous reports. Her symptoms and image findings were consistent with that of a lymphoma. However, histopathological examination of the lymph node revealed emperipolesis, a characteristic feature of Rosai-Dorfman disease. After medical treatment with steroids for 2 weeks, the size of the lymph node decreased by 50%. Since the clinical course of Rosai-Dorfman disease varies from spontaneous remission to fatal outcomes, we believe that Rosai-Dorfman disease should be considered in the differential diagnosis of patients with cervical lymphadenopathy. (J Clinical Otolaryngol 2013;24:291-295)

Keywords: 조직구; 림프구 탐식; 림프절
Keywords: Histiocytosis; Emperipolesis; Lymph node