뇌기저부 골수염으로 진행된 만성 침습성 진균성 부비동염 1예

Chronic invasive fungal sinusitis is a life-threatening disease, but encompasses a more unhurried progression of illness, in contrast with acute invasive fungal sinusitis. This case is a fungal sinusitis with skull base osteomyelitis and meningitis progressed from fungal ball past years. Fungal ball is easily treated by endoscopic sinus surgery and rarely progress to invasive type. If invasive fungal sinusitis is not timely diagnosed by histopathologic evidence of fungal hyphae, it makes clinicians embarrassing and face poor clinical course of patient like this case. It should be noted that chronic invasive fungal sinusitis may be developed from even fungal ball in a diabetes mellitus patient and may extend to skull base osteomyelitis and meningitis. (J Clinical Otolaryngol 2010;21:89-94)