부비동비강미분화암 1예

Sinonasal undifferentiated carcinoma (SNUC) is an uncommon, highly aggressive malignancy arising in the nasal cavity or paranasal sinuses that carries a poor prognosis despite a multimodality treatment approach. Since its recognition, different treatment regimens including combined radical resection, radiotherapy, and chemotherapy have been recommended. We have experienced a tumor that developed in the upper nasal cavity including the olfactory cleft and ethmoid sinus. Based on the location of tumor development, we initially diagnosed olfactory neuroblastoma, and its biopsy results reported the tumor to be sinonasal undifferentiated carcinoma. The tumor was completely removed through craniofacial resection. The patient underwent chemotherapy and radiation therapy and was asymptomatic at 12-month follow-up. We herein report a case of sinonasal undifferentiated carcinoma with a brief review of the literature in order to alert other clinicians to this rare tumor and to expedite appropriate management. (J Clinical Otolaryngol 2009;20:100-105)