혈관운동성비염의 임상적 특징과 국소 Ipratropium Bromide의 치료 효과

Background and Objectives: Vasomotor rhinitis (VMR) has similar symptoms compared to the allergic rhinitis (AR). Many doctors still use the same AR medicine without exact diagnosis, even if the patient has VMR. The aims of this study are clinical feature of VMR and efficacy of intranasal ipratropium bromide. Materials and Method: The study was designed prospectively. The subjects consisted of 38 patients with VMR who had been treated between 2003 and 2004. Diagnostic criteria include rhinitis symptoms lasting more than 3 months, no eosinophilia in nasal smear test, and negative results for MAST and allergic skin test. The patients were treated with intranasal ipratropium bromide for 4 weeks and compared pre-treatment and post-treatment symptom scores. Results: Chief complaints of the patients was nasal obstruction, followed by rhinorrhea, sneezing, and itching. After treatment, the average symptom score of rhinorrhea was significantly improved from 1.5 to 0.5 (p<0.05) and 21 patients (84%) general symptom score was decreased. Conclusion: Ipratropium bromide is useful medicine for treatment of VMR, especially to control of rhinorrhea. (J Clinical Otolaryngol 2005;16:235–239)